Live Better
& Longer

HELP Therapeutics is a clinical-stage regenerative medicine company dedicated to the research, development, and commercialization of cell therapy products for the treatment of degenerative diseases. Established in 2016, our mission is to harness the transformative potential of stem cell technology to develop innovative therapies that address critical unmet medical needs.

Our core technology is built upon allogeneic, off-the-shelf iPSC-derived cell therapy, supported by a fully automated cell manufacturing platform designed to deliver scalable, standardized, and accessible treatments to patients worldwide. We are building a robust pipeline of product candidates, anchored by our Core Product, HiCM-188 — an iPSC-derived cardiomyocyte injection developed for the treatment of advanced heart failure.

HiCM-188 is the first and currently the only iPSC-derived cardiomyocyte therapy to receive IND clearance in both China and the United States. We are currently conducting a Phase II clinical trial in China and preparing to initiate a Phase I/IIa trial in the United States.

At the heart of our work is a commitment to transforming lives through science. Our multidisciplinary team of scientists, clinicians, and industry experts remains steadfast in its mission to advance the frontiers of regenerative medicine and bring meaningful hope to patients confronting degenerative diseases.

Our Road

2016

Help Therapeutics was founded by Dr. Jiaxian WANG

2017

The iPS Cell Model Bank for Intractable Diseases was established

2018

Our strategy was made for developing iPSC-derived cardiomyocytes for heart failure indication

2019

The First in Human study of HiCM-188 was initiated

2020

1-year follow-up study of HiCM -188 was reported by Nature

The first certification of iPSC-drived cardiomyocytes was issued by China National Institutes For Food and Drug Control (NIFDC)

2021

Help Therapeutics raised hundreds of millions (CNY) / Series C

The first clinical approval of iPSC based cell therapy was filed by National Health Commission in China

HELP Cell-foundry, a cutting edge automatic facility for cell production and QC, was launched complying with US & Sino GMP standards

2022

Joint labs with University of Macau and Oujiang Laboratory were established

HiCM -188’s IND application was submitted to CDE

Our team
wangjiaxian
Dr.Eugene, J. WANG
Founder & CEO, Help Therapeutics Co., Ltd.

Achievements of
Stem Cell Innovation

🏅️

Two grants of the State National Key R&D Programs
2022: Vascular reconstraction and its application in ischemic heart failure based on stem cell and biomaterial engineering
2017: Stem cell therapy for heart failure

🏅️

The Technology & Innovation Exhibition of China 13th Five-Year Plan (2021)
Cardio-regeneration cell therapy
Integrated multi-scale & automatic cell-foundry platform

🏅️

Progress of HiCM-188
The first domestic iPSC-driven clinical trial filed by National Health Commission of China: MR-32-21-014649 IND approval in Jan 2023
Collaborator: Prof. Dongjin WANG, Nanjing Drum Tower Hospital

🏅️

The Project of iPSC Preservation Study collaborated with S&T institute of China National Health Commission
The standardized construction and application of human iPSC-derived cell model bank

We Are Here

Nanjing

Headquarters

Building 1, Life Science and Technology Town, No.568 Longmian Avenue, Jiangning District, Nanjing, China

Hong Kong

Hong Kong Office

Building 19W, Science Park West Avenue, Hong Kong Science Park, Hong Kong SAR, China

Shenzhen

Shenzhen Office

Phase I, Qianhai Shimao Financial Center, No. 3040 Xinghai Avenue, Nanshan District, Qianhai Shenzhen-Hong Kong Cooperation Zone, Shenzhen, China

Beijing

Beijing Office

51A, Jingyuan Art Center, No.3 Guangqu Road, Chaoyang District, Beijing, China